News from Hepatitis Week of Sept. 21, 2003 / Vol. 3 No. 38
Study: Diabetes Risk Higher for Hepatitis C Patients With Mixed Cryoglobulinaemia


Hepatitis C patients who also have mixed cryoglobulinaemia are at higher risk of developing type 2 diabetes, according to a study reported in the September 16 on-line issue of Rheumatology.

Mixed cryoglobulinaemia is a disease that involve inflammation in blood vessels. As many as half of chronic hepatitis C patients have detectable cryoglobulins. Only a small fraction of such patients achieve long-term recovery after interferon therapy.

Researchers from the University of Pisa School of Medicine in Italy studied 229 hepatitis C patients with mixed cryoglobulinaemia and compared them with 217 patients in a control group who did not have hepatitis C.

The prevalence of type 2 diabetes was more than two times as great (14.4 vs 6.9 percent) in the hepatitis C patients with mixed cryoglobulinaemia as it was in the control participants.

This occurred despite the fact that the diabetic hepatitis patients with mixed cryoglobulinaemia were leaner and had lower cholesterol and blood pressure levels than the diabetic patients in the control group.

Other sources: Rheumatology