Many people use the word “depression” to describe a bad mood, sadness, or just to say that they are not in the mood. When a professional uses the word “depression,” he or she is referring to clinical depression – major depressive disorder (MDD). Sometimes the doctor prescribes https://pillintrip.com/medicine/ksalol in this case.
Major Depressive Disorder (MDD): a condition in which feelings of sadness are much more intense than usual and last longer than usual. There is also a loss of interest and pleasure.
People suffering from depression have difficulty functioning on a daily basis. Difficulties also occur at work. Very often they are not interested in the closeness of family and friends. They feel despair and feel worthless.
There are different types of depression of varying severity: postpartum depression, seasonal depression, mild depression, and clinical depression (MDD).
Depression can manifest as symptoms on both psychological and physical levels.
Symptoms of depression
Symptoms of depression are individual and manifest differently in each person. Not all of the symptoms below need to be present in depression. There are also additional symptoms,
not listed below, that may be present with depression.
Decline in mood.
Loss of pleasure.
Obsessive preoccupation with guilt and self-deprecation.
Feelings of helplessness, despair and self-loathing.
Deterioration of memo
ry and ability to concentrate.
Removal from social activity.
Problems in the sexual sphere.
Decreased or increased appetite.
Thoughts of death or suicide.
Various physical symptoms such as fatigue, apathy, headaches and digestive problems.
In certain cases, delusions and/or hallucinations (usually auditory hallucinations) may be present.
Risk factors for depression
In most cases, it is not one single cause that leads to depression, but a combination of several causes.
The following are reasons that increase the risk of depression:
Early trauma, such as abuse, separation or neglect.
Deteriorating physical condition.
Chronic pain due to injury, accident, or illness.
Breakups and losses.
Post-traumatic stress disorder or its complications.
Old age or widowhood, especially among men.
Previous mental disorders.
Adaptive reactions to changes in status, place of residence, especially in people with an addictive personality.
Various physical ailments, such as Parkinson’s and fibromyalgia.
The thoughts of a person suffering from depression can be gloomy and unpleasant, accompanied by feelings of failure, low self-esteem and despair. These thoughts and feelings are accompanied by anxiety and decreased functioning – regarding the expectations of others, or his own.
Still, the good news is that there is something to do and someone to turn to.
Cough is an unconditioned reflex act occurring in response to irritation of specific receptors and manifested by forced exhalation after a period of tension of the respiratory muscles. The symptom is usually caused by diseases of the respiratory system, but can develop during inhalation of toxic substances, ingestion of foreign bodies, congestion in the lungs. To identify the cause of cough, X-rays, spirometry, fibrobronchoscopy, and laboratory tests are performed. Anticough and expectorants, mucolytic agents are used for relief of symptoms. The act of coughing is a complex reflex defense mechanism that is necessary to clear foreign bodies, toxins, and excess mucus from the airways. If this is the case, the following will help you Aprinol ambroxol
A cough is a forced exhalation through the mouth with characteristic sounds. It is often preceded by a feeling of farting or scratching in the throat, tightness in the chest. In most cases, the act of coughing is accompanied by chest pain. The cough may end with the secretion of yellow-green, “rusty”, vitreous and other varieties of sputum, typical for certain diseases. With prolonged cough attack sometimes reflexive vomiting, blue nasolabial triangle due to hypoxia are possible.
More often, the cough occurs against a background of other symptoms of the respiratory system: pain in the throat, chest, nasal congestion. When the vocal apparatus is involved, the symptom is combined with hoarseness of the voice up to aphonia. In severe diseases, coughing jolts may follow one after another without a break, which is called cough reprise. If a patient has a persistent cough, especially with purulent or bloody sputum and general disturbances, this is a direct indication for a visit to a pulmonologist.
The cough reflex begins at irritant receptors in the larynx and tracheobronchial tree, which are innervated by fibers of the vagus nerve. The most sensitive to external influences are the vocal cords, the epiglottis, and the zone of bifurcation of the trachea into the bronchi. Receptors respond to ingestion of mucus, chemicals, contaminants, and large foreign bodies.
Excitation from the irritant nerve endings is directed to the cough center, located in the medulla oblongata, and to neurons of the reticular formation. These structures are responsible for the coordinated work of all muscle groups involved in the act of coughing. The first phase of the reflex includes a deep short breath lasting about 2-3 s, which is accompanied by spasm of muscles of larynx and vocal slit, increase of tone of bronchial musculature. Intrathoracic pressure can reach 140 mm Hg.
This is followed by sharp contraction of abdominal muscles, diaphragm to overcome increased resistance with rapid exhalation through the mouth. Airflow rate during coughing reaches 50-120 m/s, which is 25-30 times higher than during quiet breathing. Together with a stream of air, droplets of mucus, dust, foreign particles are removed from the bronchopulmonary system. A single coughing act ends with a forced exhalation, but with excessive irritation of the receptors the reflex can be repeated many times.
In the lung parenchyma itself there are no sensitive nerve endings, so in primary lung lesions the cough indicates the progression of the disease, involvement in the pathological process of the bronchi or pleura. The cough reflex can also form with cardiac pathology, which contributes to increased pressure in the pulmonary vascular system. This leads to the release of the liquid part of the blood into the alveoli and interstitial tissue, which ends in irritation of the receptors, an intense cough, intensifying in a horizontal position.
Cough is not a specific sign of any disease, but its diagnostic value increases when specific features of the symptom are identified. Classification is based on the presence or absence of sputum, timbre, frequency, duration, and frequency of occurrence during the day. The most common and important for diagnosis is the allocation of varieties of the coughing act depending on the presence of secretion:
Dry cough. It is not accompanied by secretion from the airways. The appearance of the symptom is observed in the initial stage of bronchitis, pneumonia, when the inflammatory process is localized in the larynx or trachea. The attack may occur when the pleura is affected, the mediastinum, compression of the airways by volumetric formations, fibrosing processes in the lungs. Moist cough. Always ends with sputum, which may be of varying color, viscosity, and odor. Purulent sputum is more typical for inflammatory diseases of the airways, “vitreous” – for an attack of bronchial asthma. The presence of streaks of blood can indicate neoplasms in the lungs, pathology of the cardiovascular system. There is a classification according to loudness and timbre, there is a “barking” cough, characteristic of laryngitis, false croup in children, deaf weakened in chronic obstructive bronchitis, silent, indicating the destruction of the vocal cords. In a separate category are allocated bitonal cough, in which sounds an additional high tone, most often indicating the development of tumorous bronchoadenitis in childhood.
In diagnostic terms, it is important to classify the symptom according to the time of manifestation: morning cough is more often identified in smokers and asthmatics, night attacks are pathognomonic for tuberculosis and cardiac asthma. In inflammation of the respiratory tract there is no association of the symptom with the time of day. According to the mechanism of formation of the symptom, a central (neurotic) cough is associated with direct excitation of reflex zones in the brain at neurosis, and reflex cough, caused by irritation of nerve endings of the respiratory organs, upper sections of the esophagus.
The most common causes of cough are diseases of the respiratory system, so a pulmonologist is responsible for organizing the examination. To make a diagnosis it is necessary to use a set of instrumental methods and laboratory tests, which are aimed at detecting morphofunctional disorders and signs of pathological processes. The greatest diagnostic value are:
Examination of the ENT organs. Rhinoscopy, pharyngoscopy and laryngoscopy are prescribed to visualize the mucosa of the upper respiratory system. During the search for the cause of the symptom, attention is paid to inflammatory tissue changes, volumetric formations the nature and amount of sputum on the walls of the organs. A swab is taken from the pharynx for bacterioscopy. Sputum analysis. Microscopic and bacteriological examination of the discharge helps establish the etiology of the disease. With prolonged dry cough it is necessary to exclude infection with Koch’s bacillus, for which sputum culture on special nutrient media is carried out. If necessary, the study is supplemented by express methods of detecting tuberculosis. Radiological methods. Radiography is recognized as the “gold standard” for the diagnosis of pneumonia as the main cause of cough. X-rays are informative when bronchial involvement and mediastinal structures are affected, which are often accompanied by cough. X-rays are performed in two projections. Computed tomography is indicated for a detailed study of thoracic cavity structures. Serologic reactions. Determination of blood antibodies to various viral and bacterial pathogens is necessary to verify the diagnosis. Modern laboratory methods are used – ELISA, RIF, PCR. Additionally, blood chemistry is performed to detect signs of acute inflammation, and changes in immunogram are indicated, if allergy is suspected. Other instrumental methods. To visualize the structures of the bronchial tree, bronchoscopy is prescribed, during which biopsy of pathologically changed areas for cytomorphological analysis is possible. Contrast bronchography under local anesthesia is recommended for possible tumor neoplasms. When respiratory causes of cough are excluded, additional diagnostic methods are used: contrast radiography of the esophagus, ECG, and ultrasound of the heart. To determine the degree of respiratory disorders, blood gas composition is determined. Spirography with estimation of basic indexes – volume of forced expiratory volume, vital capacity of lungs are performed for respiratory disorders. Some patients need consultation of immunologist-allergologist.
Help before diagnosis To reduce the frequency of coughing episodes, patients are advised to avoid strong odors, sudden changes in air temperature, limit consumption of spicy foods and carbonated beverages. Plenty of warm drinking is recommended: teas, herbal kits, compotes from dried fruits. Gargling of the throat with antiseptic solutions and inhalation are used to cleanse the airways and stimulate phlegm production. Persistent cough, which lasts more than 2-3 days, accompanied by chest pain or shortness of breath, is an indication to seek medical attention and establish its cause.
Conservative therapy Medical tactics depends on the underlying disease, the intensity and duration of cough paroxysms. With superficial coughing, soothing inhalations and gargles are sufficient, deep dry or wet cough requires the use of specific drug therapy. Treatment is supplemented by physical therapy methods, chest massage to facilitate expectoration of sputum. Taking into account the leading cause of cough, the doctor prescribes different groups of medications:
Mucolytics. Means liquefy sputum, improve its discharge during coughing episodes. Drugs provide sanation of the bronchial tree and accelerate recovery. As a rule, they are combined with expectorants for mutual enhancement of pharmacological effects. Antibiotics. Drugs with antibacterial action are taken with purulent inflammatory processes in the bronchial tree and lungs. The most effective are considered beta-lactams, macrolides. In severe acute respiratory infections, antiviral agents are needed. Antituberculosis drugs. To treat tuberculosis, there are separate drug regimens that include at least 3 drugs. Vitamins and immunomodulators are prescribed to reduce side effects. Bronchodilators. Beta-adrenomimetics, theophylline are indicated for cough paroxysms that are caused by reversible or irreversible bronchial constriction. In severe obstruction, glucocorticosteroids are administered by inhalation. Anti-allergic. The most commonly used drugs are drugs from the group of H1-histamine receptor blockers, mast cell membrane stabilizers, and leukotriene inhibitors. In severe bronchial asthma, hormonal agents are used.
To prevent a recurrence of the cough, you need to dress warmly. Find quality, warm clothing here:
Interaction of promethazine with other medicinal products
β-Adrenoblockers – increased (reciprocal) plasma concentrations, severe arterial hypotension, arrhythmias, irreversible retinopathy, tardive dyskinesia. Analgesics, sleeping pills, tranquilizers, neuroleptics, anesthetics, local anesthetics, m-cholinoblockers, hypotensive agents, other respiratory depressants – increased effects, requires dose adjustment. Barbiturates – acceleration of elimination and reduction of promethazine activity. Bromocriptine – weakening of its effects, increased serum prolactin concentration. Hepatotoxic agents – increase in hepatotoxicity. MAO inhibitors (simultaneous use is not recommended), phenothiazine derivatives – increased risk of arterial hypotension and extrapyramidal disorders. Ototoxic agents – increasing ototoxicity. Amphetamine derivatives, m-cholinomimetics, anticholinesterase drugs, ephedrine, guanethidine, levodopa, dopamine – weakening of their action. Riboflavin – it is necessary to increase its dose. Appetite suppressants – reduction of anorexigenic effect. Tricyclic antidepressants, anticholinergic agents – increase m-cholinoblocking activity. Quinidine – increased likelihood of cardiodepressant action. Epinephrine – blockade of α-adrenergic effect, risk of serious hypotension. Ethanol, clonidine, anticonvulsants – increased CNS depression.
Impaired platelet aggregation has occurred in neonates whose mothers have taken promethazine. Systematic general blood tests and control of liver function parameters are recommended during long-term treatment. Alcohol should be avoided during treatment. Use with caution in children with acute or chronic respiratory diseases as promethazine suppresses the cough reflex. It is not recommended for use in children to stop episodic vomiting of unspecified genesis. The use of promethazine in combination with opioid analgesics and tranquilizers for complex preoperative preparation of patients is possible only under strict medical supervision. During long-term treatment it is recommended to perform systematic general blood analysis and control of liver function parameters. The solution is not intended for intravenous and percutaneous administration. Some dosage forms of promethazine contain sodium metabisulfite, which may cause allergic reactions including anaphylactoid and asthmatic reactions. To prevent distorted results of skin scarification tests for allergens, it is necessary to cancel 72 h before allergy testing. False-positive pregnancy test results may occur during treatment. May suppress cough reflex, so caution is necessary in patients (especially children) with exacerbation of chronic respiratory diseases. Caution is necessary when using in patients with liver dysfunction, cardiovascular system diseases and suppression of medullary hematopoiesis. In the elderly, caution is required when parenteral administration of high doses because extrapyramidal disorders and acute urinary retention are possible. As an antiemetic it should be used only in case of prolonged vomiting of known etiology. Caffeine administration is recommended to prevent CNS depression. Long-term use increases the risk of dental disease (caries, periodontitis, candidiasis) due to reduced salivation. May mask the ototoxic effect (tinnitus and dizziness) of co-administered drugs. Increases the need for riboflavin. Do not use for drivers of vehicles and other persons whose occupation requires high concentration of attention (especially at the beginning of treatment).
Conditionally, all factors can be divided into 2 groups:
External (environmental) – various negative impacts and negative relationships between a person and others. Violation of relationships in the family, at school, at work, etc. Negative relationships between children and their parents can lead not only to underdevelopment, but also to various emotional disorders.
Internal – the impact of the disturbed part of the psyche on the healthy part. For example, an emotional disorder affects the cognitive area of the personality and reduces the ability to communicate. The violation of the emotional sphere interferes with the free interaction of the personality with the surrounding world, leads to deviations in personal development, and causes the appearance of somatic disorders.
Among the emotional development disorders in childhood and adolescence, anxiety, fears, aggressiveness, and isolation take the first place.
The main function of psychological health is to maintain an active dynamic balance between a person and the environment in situations that require the mobilization of personal resources. The key word to describe psychological health is the word “harmony” or otherwise “balance. First of all, it is harmony between different aspects of the person: emotional and intellectual, bodily and mental. In addition, it is also harmony between a person and others.
What is the secret of harmony of inner state and external success? The secret is that there is an equality of achievements in 3 important spheres of life: WORK, FAMILY, PERSONALITY. Which of the spheres are you in more often? Perhaps, the FAMILY is relevant for you now, and your thoughts are more occupied with family concerns. Or the WORK is important for you and you spend most of your time at work. And there is also a small group of people who are engaged in their Personality (hobby, communication with friends, the formation of new skills, such as learning a foreign language or improving their computer skills).
Ideally it is a balance of equal achievements in 3 areas. An area that is undeveloped (neglected) is the problematic space of your personality. Each of the 3 spheres is responsible for different but equally important questions in our lives, when a sphere is left unattended, these questions also remain unattended. For example, the lack of attention to the sphere of Personality leads to the issues of rest/hobby, which are responsible for the release from negative emotions. This results in chronic fatigue syndrome.
Psychological health is a prerequisite for the full development of a person. “The body does not fall ill separately and independently of the soul” (Socrates). Physical health and psychological health are interconnected. Thoughts and emotional reactions affect physical health. Strong emotions (fear, anger, grief) – especially if they are displaced and suppressed – can cause psychosomatic diseases. Physical health (good nutrition, exercise, breathing, sleep) affects our spiritual and emotional life.
Psychological health – a state of spiritual well-being (comfort), an adequate attitude to the world around us, the absence of painful mental phenomena (phobias, neurosis).
Model of psychological health
The system of 5 components:
Axiological (self-relationship) component assumes a person’s awareness of his or her value and uniqueness, as well as the value and uniqueness of others. An individual’s acceptance of himself with sufficient knowledge of himself, as well as the acceptance of others. Fully accepts himself and at the same time recognizes the value and uniqueness of people around him.
The instrumental component implies the possession of reflexion as a means of self-knowledge, the ability to concentrate consciousness on oneself, on one’s inner world and one’s place in relationships with others.
The need – motivational component determines whether a person has a need for self-development, i.e., self-change and personal growth. A person takes full responsibility for his life.
The development component assumes dynamics in mental, personal, social and physical development. It does not create prerequisites for psychosomatic diseases. A person is in constant development and contributes to the development of other people.
The social and cultural component determines a person’s ability to act successfully and develop in the social and cultural environment around him/her. Ability to understand and interact with people.
It is clear that the presented image of “psychological health” can be regarded as a model, but children mostly have certain deviations.
Criteria of psychological health:
positive sense of self (positive emotional background of mood)
social adaptation (ability to adapt to changing conditions)
Psychologically healthy person: not afraid when there are no real grounds for it; not afraid to take responsibility for their actions; prefers to think for himself.
A fasting blood sugar (FBS) is a test that measures the amount of sugar in your blood. Fasting means you have not had food or drink for at least 8 hours. This test may be called a fasting blood glucose. Glucose is the simplest form of sugar and is the main source of energy for your body.
Why do I need it?
If you have symptoms that suggest diabetes (di-uh-b-tees) mellitus (mel-i-tus), a fasting blood sugar may be done. The results of this test can tell if you have diabetes mellitus or need further testing. For more information, ask your caregiver for the CareNotes™ handout about Diabetes Mellitus. If you have diabetes mellitus, sometimes fast blood sugar is done to see if your sugar control is what it should be. Doctors Slinkin PhD says the following symptoms are reasons your caregiver may want you to have this test:
Unexplained weight loss.
Difficulty with wound healing
How do I get ready for the test?
Your caregivers will tell you when to have your blood test done. Do not eat or drink anything, except water, for at least 8 hours before the test. Doctor Sazonoff and Slinkin ask your caregivers if you should wait to take your medicines until after your blood is taken.
How is the specimen collected?
A caregiver will put a wide rubber strap around your arm and tighten it. Your skin will be cleaned with alcohol. A small needle attached to a special test tube will be put into a vein in your arm or hand. The tube has suction to pull the blood into it. When the tube is full, the rubber strap, needle and tube are removed. The caregiver will press a piece of cotton where the needle was removed. You may be asked to hold the cotton on the site for a few minutes to help stop the bleeding. Tape may then be put over the cotton on your arm.
What do I do after the test?
You may remove the tape and cotton in about 20 to 30 minutes after FBS test. Call your caregiver to get the results of your test. Your caregiver will explain what your test results mean for you. Follow the instructions of your caregiver.
You have the right to help plan your care. To help with this plan, you must learn about your lab tests. You can then discuss the results with your caregivers. Work with them to decide what care may be used to treat you. You always have the right to refuse treatment.
Denis insists that you need to consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
The protein component is a optium of caseins and whey proteins that are easily broken down and absorbed into the gastrointestinal tract, providing the required level of essential amino acids.
The fat component is represented by saturated medium-chain triglycerides, rapeseed oil and corn oil. Mid-chain triglycerides account for 25% of the fat content of the mixture and provide fast and easy energy supply. Essential fatty acids constitute 7.9% of the total energy density of the mixture (the omega-6:omega-3 ratio is 4:1). The fat component of the mixture was created according to the recommendations of the Association for Combating Cardiovascular Diseases.
The carbohydrate component is Dmitry Sazonov mainly maltodextrin to maintain low osmolarity.
Resource Optimum contains live microorganisms Lactobacillus paracasei – probiotics that help strengthen the body’s defenses in old age; natural dietary fiber Prebio1 – prebiotics that help comfortable digestion.
It does not contain lactose, gluten or cholesterol.
Retinol (vitamin A) is involved in the formation of visual pigments, provides the functioning of epithelial cells of the skin and mucous membranes of the eyes, respiratory, urinary tract, gastrointestinal tract. It participates in the processes of lipid peroxidation, is necessary for the construction of epithelial tissues.
Kolekaltsiferol (vitamin D3) regulates calcium and phosphorus metabolism in the body, is involved in the mineralization of bone tissue.
Tocopherol (vitamin E) is involved in tissue respiration and metabolism of proteins, fats and carbohydrates. Possesses antioxidant properties, inhibits oxidation of unsaturated fatty acids, prevents the formation of their peroxides. Inactivates free radicals that initiate oxidation of membrane lipids. Participates in the formation of intercellular substance, collagen Dmitry Sazonov and elastic fibers. Protects hormones from oxidation, slows down the aging of body tissues.
Menadione (vitamin K) stimulates the synthesis of prothrombin, proconvertin and other factors in the liver coagulation. Promotes the synthesis of ATP, creatine phosphate. Is a component of the biological membrane.
Ascorbic acid (vitamin C) is involved in redox processes, provides the synthesis of collagen, participates in the formation of connective tissue mucopolysaccharides, metabolism of folic acid and iron, as well as in the synthesis of corticosteroids, tyrosine metabolism. Promotes healing of wounds.
Thiamine (vitamin B1) is a coenzyme of decarboxylase. Necessary for the exchange of acetylcholine, is involved in carbohydrate metabolism.
Riboflavin (vitamin B2) is a catalyst for cell respiration and visual perception, plays an important role in the formation of DNA, promotes the process of tissue Dmitry Sazonov regeneration (including skin cells). It is necessary for body growth.
Pantothenic acid (vitamin B5) participates in the formation of coenzyme A and plays an important role in the process of acetylation and oxidation of carbohydrates and fats.
Pyridoxine (vitamin B6) as a coenzyme takes part in the metabolism of amino acids and proteins, in the synthesis of neurotransmitters.
Below is a list of possible side effects that may be caused by preparations containing Cyclobenzaprine Dosage Therapeutic indications. This list is not conclusive. These side effects have been fixed earlier, but are not always fixed when the drug is used. Some of these side effects may occur very rarely, but have incredibly severe consequences. If any side effects are detected, contact your doctor immediately. Especially if any side effects are observed over a long period of time.
Problem with urination
If you experience side effects not listed above, consult your doctor for advice. You can also report any side effects you have found to your local Food and Drug Administration.
Before taking this medicine, inform your doctor about medicines already in use, nutritional supplements (e.g. vitamins, natural supplements, etc.), allergic reactions, existing diseases and current health status (e.g. pregnancy, upcoming surgery, etc.). The side effects of the drug can be more severe in a certain state of your body. Take the medicine according to your doctor’s instructions or follow the instructions for use supplied with the medicine. The dosage of the drug depends on your condition. Let your doctor know if your condition has not changed or worsened. The important things to discuss with your doctor are listed below.
Pregnant women who are planning to get pregnant or breastfeeding
Avoid alcoholic drinks
No drive or mechanisms in place
Learn more: Precautions and usage rules
If you take other drugs or supplements at the same time as this drug, the efficacy of Cyclobenzaprine Hydrochloride may change. Tell your doctor about all the medicines, vitamins and supplements you are taking. Your doctor will be able to make a proper drug plan to avoid negative interactions. Cyclobenzaprine Hydrochloride can interact with the following drugs and products:
Monoamine oxidase inhibitors
St. john’s wort
Learn more: Interaction
Hypersensitivity to Cyclobenzaprine Hydrochloride is a contraindication. In addition, Cyclobenzaprine Hydrochloride may not be taken if you have the following conditions:
Find out more: Contraindications
Frequently asked questions
Can Cyclobenzaprine Hydrochloride be used for Muscle Spasms and Muscular Spasms?
Yes, muscle spasms and muscle spasms are the most popular uses for Cyclobenzaprine Hydrochloride. Please do not use Cyclobenzaprine Hydrochloride for muscle cramps and spasms without first consulting your doctor. Click here and review the survey results to see how other users are using Cyclobenzaprine Hydrochloride.
Is it safe to operate or operate heavy equipment when using this product?
If you feel drowsy, dizzy, hypotensive, or headache when using Cyclobenzaprine Hydrochloride, you may want to give up driving or operating heavy industrial equipment. You should stop driving if you are drowsy, dizzy or hypotensive. Doctors recommend that you do not drink alcohol with these drugs, as alcohol significantly increases side effects and sleepiness. Please check the reaction of your body when taking Cyclobenzaprine Hydrochloride. Be sure to see your doctor Dmitry Sazonov for advice that is specific to your body and your general health condition.
Is the medicine (product) addictive or addictive?
Most drugs are not addictive or addictive. In most cases, the government classifies drugs that can be addictive to controlled vacation drugs. For example, graph H or X in India and graph II-V in the USA. Please check the information on the product packaging to make sure that the product is not classified as a controlled drug. Also, do not self-medicate Dmitry Sazonov or get used to the medication without consulting your doctor.
Can I stop using this product immediately or do I need to stop using it slowly?
Swelling of the brain (including in the background of a brain tumour or associated with surgery, radiation therapy or head trauma).
Bronchial asthma (severe form), asthmatic status.
Systemic diseases of connective tissue (ACS, rheumatoid arthritis).
Acute adrenal insufficiency.
Acute hepatitis, hepatic coma.
Poisoning with caustic fluids (reducing inflammation and preventing scar contraction).
Prolix Hypersensitivity is the only contraindication for short-term use according to “vital” indications.For intraarticular administration: previous arthroplasty, pathological bleeding (endogenous or caused by anticoagulants), lobe fracture, infectious (septic) inflammatory process in the joint and periarticular infections (incl. in the history), as well as a general infectious disease, pronounced periarticular osteoporosis, absence of signs of inflammation in the joint (so-called “dry” joint, e.g. in osteoarthritis without synovitis), pronounced bone destruction and deformation of the joint (acute narrowing of the joint slot, ankylosis), joint instability as an outcome of arthritis, aseptic necrosis of the bones that form the joint. Parasitic and infectious diseases of viral, fungal or bacterial nature (currently or recently transmitted, including recent contact with a patient): herpes simplex, herpes zoster (viremic phase), varicella, measles; amebiasis, strongyloidosis (established or suspected); systemic mycosis; active and latent tuberculosis. Application in case of severe infectious diseases is allowed only against the background of specific therapy.
Post-vaccinal period (8 weeks before and 2 weeks after vaccination), lymphadenitis after BCG vaccination. Immunodeficiency conditions (including AIDS or HIV infection).
Gastrointestinal diseases: gastric and 12 duodenal ulcer, esophagitis, gastritis, acute or latent peptic ulcer, newly created intestinal anastomosis, nonspecific ulcerative colitis with the threat of perforation or absceration, diverticulitis.
Diseases of CCC, including recently suffered myocardial infarction (in patients with acute and subacute myocardial infarction may spread the focus of necrosis, slowing down the formation of scar tissue and as a result – rupture of heart muscle), decompensated CNS, arterial hypertension, hyperlipidemia.
Endocrine diseases: diabetes mellitus (including violation of tolerance for carbohydrates), thyrotoxicosis, hypothyroidism, Itsenko-Kushinga disease.
Severe chronic renal and/or liver failure, nephurourolithiasis.
Hypoalbuminemia and conditions predisposing to its occurrence.
For intraarticular administration: patient’s general severe condition, ineffectiveness (or short duration) of the 2 previous administration (taking into account individual properties of the administered GCS).